Endocrine Abstracts

A 20-year-old female first presented in 2013 with a six-month history of feeling faint, palpitations, weight loss and oligo-amenorrhoea. She was found to have autoimmune thyrotoxicosis with a fT3 15.2, fT4 43.3, TSH <0.05 and TPO antibodies strongly positive. She was subsequently commenced on Carbimazole 20 mg once a day and was biochemically euthyroid within 6 months. Interestingly, however, she continued to lose weight and remained oligo-amenorrhoeic. ...

A 20-year-old female first presented in 2013 with a six-month history of feeling faint, palpitations, weight loss and oligo-amenorrhoea. She was found to have autoimmune thyrotoxicosis with a fT3 15.2, fT4 43.3, TSH <0.05 and TPO antibodies strongly positive. She was subsequently commenced on Carbimazole 20 mg once a day and was biochemically euthyroid within 6 months. Interestingly, however, she continued to lose weight and remained oligo-amenorrhoeic. ...

Case history: A 20-year-old female first presented to our endocrine clinic in 2013 with a 6-month history of feeling faint, palpitations, weight loss and oligo-amenorrhoea. She was found to have autoimmune thyrotoxicosis with a fT3 of 15.2, fT4 43.3 and TSH <0.05. Her TPO antibodies were strongly positive. She was subsequently commenced on Carbimazole 20 mg once a day and was biochemically euthyroid within 6 months. Interestingly, however, she continued to lose weight and ...

Case history: A 45-year-old male was referred to Endocrinology from the Infectious Diseases clinic for investigation of possible adrenal insufficiency. The patient had multiple co-morbidities including asthma, hepatitis B and HIV. The patient’s GP had introduced a fluticasone inhaler to control the symptoms of his asthma, however when the patient was seen in Infectious Diseases clinic as an interaction with his protease inhibitor (atazanavir) was suspected. A random corti...

Case History: A 71-year old male, who had been on amiodarone therapy for many years, was receiving Levothyroxine therapy due to amiodarone-induced hypothyroidism. He was subsequently found to have thyrotoxicosis, which remained after levothyroxine discontinuation. He had type 2 diabetes and ischaemic cardiomyopathy and had an implanted cardiac defibrillator due to multiple VT arrests. Amiodarone therapy had contributed to stabilisation of his cardiac arrhythmias and had contin...

A 71-year-old man was diagnosed with poorly differentiated T4N0M0 gastric adenocarcinoma. He received neoadjuvant chemotherapy, followed by elective subtotal gastrectomy. Mean arterial pressure was maintained above 70 mmHg throughout the 5-hour operation. On post-operative day 3, the patient became confused, pyrexial, hypotensive with new-onset atrial fibrillation. CT head was unremarkable and CT chest/abdomen/pelvis (CAP) showed bilateral pleural effusions with normal adrenal...

We report a case of two incidental lesions, a benign adrenal schwannoma and cerebral meningioma. There are no cases in the literature to link de-novo adrenal schwannoma and meningioma in patients. This case highlights the importance of multidisciplinary working to ensure expedited management in such cases.A 76 year old gentleman presented to ED with a seizure and a community-acquired pneumonia. Past medical history included atr...

We present a case of a middle-aged lady with clinical features suspicious of Addisons, however an initial false negative short synacthen test (SST), resulted in delay of diagnosis.Case: A 62-year-old lady presented to ED with a month history of generalised malaise, weakness, dizziness and vomiting. She had a background of type2 diabetes mellitus, previous left parathyroidectomy for primary hyperparathyroidism and B-thalassaemia trait. Admission bloods in...

We report a case of two incidental lesions, a benign adrenal schwannoma and cerebral meningioma. There are no cases in the literature to link de-novo adrenal schwannoma and meningioma in patients. This case highlights the importance of multidisciplinary working to ensure expedited management in such cases.A 76 year old gentleman presented to ED with a seizure and a community-acquired pneumonia. Past medical history included atr...

We present a case of a middle-aged lady with clinical features suspicious of Addisons, however an initial false negative short synacthen test (SST), resulted in delay of diagnosis.Case: A 62-year-old lady presented to ED with a month history of generalised malaise, weakness, dizziness and vomiting. She had a background of type2 diabetes mellitus, previous left parathyroidectomy for primary hyperparathyroidism and B-thalassaemia trait. Admission bloods in...